In a study of 36 women with yeast vaginal infections, monolaurin was effective against Candida albicans. While this may not be necessary or common, it should not be harmful. Breastfeeding provides infants with nutrients for growth and development as well as immune protection to compensate for the immature and inexperienced defense mechanisms at mucosal surfaces [Ref #28]. Many holistic doctors report that they see improvement in clients overall sense of well-being. (2) Sterile water q.s., if needed, to total 1 cc volume for cats less than 2.5 kg (5 lb). Putting it into soft pet foods will help them eat the pellets. In bacteria, monolaurin combined with monocaprin, lauric acid, or monomyristin had better results against Staphylococcus aureus [36]. Antibiotic resistance has become a worldwide problem. The scientist who discovered monolaurin markets it under the brand name Lauricidin. Monolaurin has shown antibacterial and antiviral effects when examined in test tubes and culture dishes, which is referred to as in vitro testing. Our bodyadds glycerol to other coconut acids, as well, and converts them into the monoglycerides. AAHA Amplify: A Group Accreditation Program, Why pet owners should seek AAHA-accredited practices, Infection Control, Prevention, and Biosecurity, FREE WEBINAR: AAHA Senior Care Guidelines, Distance Education Veterinary Technology Program (DEVTP), AAHA Guidelines Certificate Course in Nutrition, Why De-escalation Training Is Essential for CSRs, Shining a Spotlight on Ideas that Work: Veterinary Visionaries and Beyond, Practices Celebrating Accreditation Anniversaries, AAHA Board of Directors notice of position vacancies, Notice of AAHA Board of Directors slate of nominations, Tips and Tricks for Anesthetizing Diabetic Dogs and Cats, New: Top Tips for Techs and Pet Owner Resource. Food-Induced Anaphylaxis. WebInstill 1 drop into the affected eye (s) every 6 to 8 hours as needed. Foods that link to cancer include highly processed foods, red meat, and alcohol. Monolaurin is a chemical derived from lauric acid and glycerin, and is a byproduct of coconut fat. It can be life-threatening in immunocompromised people. Based on the qualities mentioned above, monolaurin has several suggested uses. Step 2: Herpes and Shingles are external. WebGlargine (Lantus), q 12 hr based on the estimated ideal body weight of the cat and BG levels: 0.5 U/kg q 12 hr if BG > 360 mg/dL Or 0.25 U/kg q 12 hr if BG < 360 mg/dL. If one tablespoon of coconut oil were converted to 50% Monolaurin, you would need to take 6.5 teaspoons of coconut oil to achieve the amount of Monolaurin in one 600mg capsule (assuming one teaspoon of coconut oil is 0.924 g/cm3 [grams per cubic centimeter] is approximately 184.8 milligrams). Use Alphagan (Ophthalmic) exactly as directed on the label, or as prescribed by your doctor. Serotonin-producing 5-HTP supplements have become increasingly popular for their variety of health benefits. Drug Interactions and Toxicity: (2015). (We include many studies on our site.) St. Martin's Griffin, 2017. Page 4 of 26 Children (2-18 years of age): The use of ALPHAGAN P is currently not recommended in children, as several serious adverse reactions have been reported in association with the administration of brimonidine tartrate ophthalmic solution 0.2% in pediatric population. Required fields are marked *. Anyone with a coconut allergy shouldnt ingest coconut oil, but adverse effects are otherwise unlikely. Scientists investigated whether monolaurin inhibits several fat-coated viruses that infect humans and animals. People with intestinal inflammation or risk of multiple sclerosis may need to limit their consumption of coconut and MCT oil, and, therefore monolaurin [57]. Despite this, evidence suggests that the compound may have the following qualities: Monolaurin shows antibacterial effects against a range of bacteria including antibiotic-resistant bacteria called Staphylococcus aureus (Staph). Source: Carpo BG, Verallo-Rowell VM, Kabara J. Human milk fatty acid composition from nine countries varies most in DHA. We understand that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. In some experiments, the monolaurin extracts were more potent against these bacteria as compared to conventional antibiotics [Ref #31]. More weight might be placed on well-documented published research and professional medical advice which is not opinion. Natural rice powder can be used in place of these synthetics and may not cause unwanted side effects. Another study in the Journal of Drugs in Dermatology suggested that monolaurin extracts may be potent against several bacterial species that can cause skin infections, including Staphylococcus aureus and Streptococcus spp, when studied in lab settings. Lauricidin is a commercially available product. As a result, it is not yet possible to say how much coconut must be consumed to receive enough monolaurin to treat or prevent certain illnesses. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Since monolaurin is in its highest concentration in naturein mother's milk, they suspected monolaurin might be the magic bullet responsible. This product is not intended to diagnose, treat, cure, or prevent any disease. Monolaurin is a component of coconut oil. Zhang, H., Wei, H., Cui, Y., Zhao, G., & Feng, F. (2009, September). Do not consider user experiences as medical advice. Breaking down the coconut oil controversy. Our team thoroughly researches and evaluates the recommendations we make on our site. Immune Support - A proprietary blend of cat's claw, monolaurin, and 1000 IU vitamin D3 to support a healthy immune system.*. All quotes below are taken directly (verbatim) from published studies and are not the opinion of this site. The recommended dose is one drop of ALPHAGAN P in the affected eye (s) three times daily, approximately 8 hours Select one or more newsletters to continue. Source: Thormar H, Isaacs CE, Brown HR, Barshatzky MR, Pessolano T. Inactivation of Enveloped Viruses and Killing of Cells by Fatty Acids and Monoglycerides. However, higher dosages may be needed in cats with severe heart failure because of reduced renal blood flow. Monolaurin has not been evaluated by the FDA for any medical condition, while clinical studies are few. The results, however, are promising. promoting collagen growth. Unfortunately, it is difficult to estimate just how much of the lauric acid from coconut oil is converted to monolaurin, but one article suggests that it is less than 6%. Its also available online through various sellers, including Amazon. One teaspoon of our monolaurin has3,000 mg! ALPHAGAN P (brimonidine tartrate ophthalmic solution) 0.1% or 0.15% is an alpha adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.. 2 DOSAGE AND ADMINISTRATION. Monolaurin, Monolaurin benefits, Breast Milk, Monolaurin, Monolaurin benefits, Monolaurin Supplement. PLoS One. You can find monolaurin at your local health food store or vitamin shop. Better T-cell function helps the body recognize and kill bacteria and viruses. Commonly used in dogs; injection pens (in either 0.5 U or 1 U increments) available for dogs and cats. Kabara JJ. 1994 Jun 6;724:457-64. Insulin must be discarded if these changes occur. Monolaurin is a naturally-occurring fat present in both coconut oil and breast milk [1, 2]. All rights reserved. He claims that the monolaurin yield from coconut oil is no more than 3% . When microbes are destroyed by antibiotics, medications, or supplements, proteins and cytokines are released which the immune system may have an inflammatory response. People take monolaurin supplements to encourage immune health and general wellness, but theres little scientific data to back up these claims. In Alzheimers patients, the presence of herpes simplex virus type 1 (HSV1) in the brain people with the type 4 allele of the apolipoprotein E gene has been positively associated with an increased risk of Alzheimers [50]. containers. Journal of Bacteriology. Researchers are investigating if monolaurin may inactivate or destroy various fungi and yeasts. Compared with lauric acid on a molar basis, GML represented a more effective inhibitor of biofilms formed by either S. aureus or E. faecalis. [Ref #41]. Mueller, Elizabeth A., and Patrick M. Schlievert. However, theres no valid evidence to support its use as a dietary supplement. It is safe for children (ages 310) with the recommended dose being smaller30 mg, one to three times per day. 2005-2023 Healthline Media a Red Ventures Company. Virgin coconut oil (VCO) and monolaurin's objective-SCORAD severity index (OSSI) reduction and in vitro broad-spectrum activity against Staphylococcus aureus (SA) (given clinical validity here), fungi, and viruses may be useful in the proactive treatment of Atopic dermatitis (AD) colonization., Source: Verallo-Rowell, Vermn M.; Dillague, Kristine M.; Syah-Tjundawan, Bertha S. Novel Antibacterial and Emollient Effects of Coconut and Virgin Olive Oils in Adult Atopic Dermatitis. Always note the serving size and amount per serving. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. If someone is taking coconut oil as a source of lauric acid, one theory suggests that the ideal dosage may also depend on the bodys genetic ability to convert the acid into monolaurin. SelfHacked does not endorse any specific product, service, or treatment. Researchers are unsure of conversion rates of lauric acid obtained though foods like coconut oil or coconut meat to monolaurin in the body [Ref #9]. The potential interactions between monolaurin and drugs are unknown due to a lack of data. Vol:6, No:10, 2012. Antibacterial interactions of monolaurin with commonly used antimicrobials and food components [Abstract]. African Journal of Education, Science and Technology, April, 2016 Vol 3, No. Monolaurin is a chemical derived from lauric acid, a component of both coconut fat and breast milk. Cats0.5 U/kg q 12 hr if BG > 360 mg/dL.0.25 U/kg q 12 hr if BG < 360 mg/dL. Also, some other fungi and microscopic organisms may be inactivated or destroyed by monolaurin. The recommended initial level of Lauricidin is ~0.75 gram (1/4 blue scoop) or less two or three times daily for a week before increasing the amount. In mice, monolaurin worsens multiple sclerosis, in which the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between the brain and the rest of the body [57]. Some scientists believe monolaurin might be a promising antimicrobial. high blood pressure. H. Pylori (Helicobacter Pylori) is bacteria which infects the stomach and gut and can cause complications like Gastritis or even Gastro-Esophageal Reflux Disease (GERD). Read more about Taking too much Monolaurin. Monolaurin is found in coconut oil, which is an edible, non-toxic, and a standard cooking oil. Learn what studies have to say about its ability to combat conditions from acne to. Jonathan Ritter, PharmD, PhD (Pharmacology), Goat and cow milk (contain only a small percentage of lauric acid). Lauric acid converts to monolaurin in the body [4, 5]. Early South Sea Island explorers often wondered why the island nativesseemed to stay healthier than the American Indians did when Caucasianpeople mixed with them. Lauric acid levels in breast milk can vary. Commonly used in cats; not commonly used in dogs. After much research, scientistsdetermined the key to their diet was the coconut. Champaign, Ill, USA: American Oil Chemists Society; 1978. supporting the immune system. Supporters are investigating whether monolaurin may assist in weight management by killing these stored viruses, though no valid evidence has yet been published [49]. Clinical research and guidance do not include children, and therefore the safety and efficacy are unknown. The symptoms are temporary and may include: This concept may hold in people with serious infections such as syphilis, but it has also received a lot of criticism from the scientific community when people who dont have life-threatening infections talk about it [55]. In some circles, this is referred to as the Jarisch-Herxheimer reaction, a highly controversial and unproven theory, especially in the way it is referred to in popular health blogs. Check out the products in the Product Locator. 2017;12(4):e0175817. Monolaurin supplements have not been approved by the FDA for medical use. Allegedly, it also helps with skin conditions, strengthens the immune system, and balances bacteria in the gut. Some clinicians believe that for dogs, a starting dose of 0.25 U/kg q 12 hr is appropriate and 0.5 U/kg q 12 hr should be reserved for potentially challenging diabetics. sneezing. SelfDecode does not treat, diagnose or cure any conditions, Taking monolaurin in powder form, even when mixed with another substance like apple sauce, can be very unpleasant and is not well tolerated by most. Some people see a benefit from a single 600mg capsule per day, while others may take upwards of 3-5 grams. Body aches. These include several species of ringworm. Web. There is more to buying monolaurin than the capsule weight or count. You can take monolaurin with or without food and with any liquid, without impact to efficacy or absorption. St. Martin's Griffin, 2017. 2010;5: 3. If more than one topical ophthalmic product is to be used, the Our goal is to not have a single piece of inaccurate information on this website. A cell study compared monolaurin and 6 common antibiotics (including penicillin, oxacillin, and vancomycin) against bacteria causing skin infections. Unsaturated fatty acids (FAs) and monoglycerides (MGs) can be generated from triglycerides in certain foods", Source: Sun CQ, OConnor CJ, Roberton AM. , we offer a fuller spectrum of the coconut monoglycerides than other forms of monolaurin currently in the market. ncbi.nlm.nih.gov/pmc/articles/PMC5044790/, naturalmedicinejournal.com/journal/2014-05/treatment-dermal-infections-topical-coconut-oil, fda.gov/food/ingredientspackaginglabeling/foodadditivesingredients/ucm091048.htm, cocoscience.com/pdf/a_review_of_monolaurin_and_lauric_acid.pdf, Superfood or Poison? Most cats are well regulated on insulin at an average dose of 0.5 U/kg q 12 hr, with a range of 0.20.8 U/kg. Although this study did not use human participants, it did show monolaurins effectiveness at killing bacterial infection in mice. Monolaurin (also known as glycerol monolaurate) is a medium chain fatty acid formed from lauric acid. Source: Hess DJ, Henry-Stanley MJ, Wells CL. However, safety data is lacking to determine its long-term health effects, especially in higher amounts [53]. The recommended dose is one drop of . It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. We avoid using tertiary references. When you buy monolaurin, always look for: desiccant pack, cotton pack, foil safety seal, protective neckband, Lot # and Expiration Date. Web. However, 50% of mice given vancomycin and monolaurin daily survived for 30 days [5]. Retrieved 2019-07-19. Reviews (Opinion vs. Professional Research): Customer reviews should be taken with some healthy skepticism, as there are some unfortunate incidents of both positive and negative review manipulation by some competitors. Seminars in Perinatology Volume 23, Issue 3, June 1999, Pages 242-249, Verallo-Rowell, Vermn M.; Dillague, Kristine M.; Syah-Tjundawan, Bertha S. Novel Antibacterial and Emollient Effects of Coconut and Virgin Olive Oils in Adult Atopic Dermatitis. The Journal of General Virology. He recommends high doses that would be unattainable with coconut oil or other foods. Last updated on Aug 22, 2022. Assuming you get 3% monolaurin from coconut oil, that means in order to get 750mg 3x a day, one would have to consume close to 6 tablespoons a day, which is excessive. J Drugs Dermatol. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. It is safe for children (ages 3 to 10) at the recommended dose of 30 mg, one to three times per day ( 14 ). ALPHAGAN P ophthalmic solution may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. doi:10.1111/jam.12970, FDA : 21CFR184.1505 ; https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1505, Sumit NANDI, Sarbani GANGOPADHYAY, Santinath GHOSH, Production of Medium Chain Glycerides and Monolaurin from Coconut Acid Oil by Lipase-Catalyzed Reactions, Journal of Oleo Science, 2004, Volume 53, Issue 10, Pages 497-501, Released September 10, 2004, Online ISSN 1347-3352, Print ISSN 1345-8957, Pinyaphong, P., Sriburi, P., & Phutrakul, S. Synthesis of Monoacylglycerol from Glycerolysis of Crude Glycerol with Coconut Oil Catalyzed by Carica papaya Lipase. World Academy of Science, Engineering and Technology International Journal of Chemical and Molecular Engineering. WebThere are two scenarios in which negative results may occur in infected cats. 5. Milligrams per Capsule (300mg, 600mg, 800mg): Some doses of monolaurin can get quite high, so a higher capsule fill might help reduce the need to swallow multiple capsules per day. You should consult your healthcare provider for dosing guidance. You should not take so much monolaurin that you feel unwell (upset stomach, diarrhea, headache, etc.). WebStarting Dose. economy size, which is 21 oz. This loss of effect appears with a variable time of onset in each patient and should be closely monitored. Also, coconut oil contains other antimicrobial fats and compounds not found in pure monolaurin. Dr. Kabara discovered monolaurin and markets it under the brand name Lauricidin. In the lab, when monolaurin binds to the viral envelope, it makes the virus more recognizable to the immune system [17, 18]. Isaacs CE. At present, there are no other known risks or complications associated with taking monolaurin in supplement form, but that does not prove that supplements are safe either. This substance can then be capsulated and used as a dietary supplement or for other food / cosmetic purposes. Lipids. PMC. Monolaurin had no adverse effect on gut bacteria in dishes. WebTreatment is given for 5 to 7 days and is not safe for pregnant cats. Monolaurin has been listed as "Generally Regarded As Safe" by the FDA [Ref #15], stating "In accordance with 184.1(b)(1), the ingredient is used in food with no limitation other than current good manufacturing practice. Monolaurin studies show in-vitro the potential to inactivate a range of DNA and RNA enveloped viruses by purportedly breaking down the outer lipid membrane and destroying the virus. This is your body's immune response to what it thinks is an infection. Monolaurin is a dietary supplement derived from lauric acid - a medium chain fatty acrid present in coconut and palm oil. Web1 Jar is a 4-6 Week Supply 3000mg Monolaurin in a single teaspoon Health Professional-recommended and 100% Non-Toxic, Pure Nutrient, Lauricidin is safe for your entire family. Much later, Michigan State University researchersdiscovered what happened when we eat coconut. I keep monolaurin on hand for my cats, because it cures cytauxzoanosis (bobcat tick fever), which is often fatal. Allergen Warning: Contains Tree Nuts (Coconut). Note:When selecting products, veterinarians have a choice among those formulated for humans and those developed and approved by veterinary use. Our website services, content, and products are for informational purposes only. Current scientific research into monolaurin is limited. This He also insists that people need to take 3 9g of monolaurin in order to experience a significant effect. Alternative & Complimentary Therapies, December 2006. 2016. [Ref #: 16, 17, 18]. epinephrine ophthalmic, latanoprost ophthalmic, timolol ophthalmic, pilocarpine ophthalmic, brimonidine ophthalmic, Lumigan, Combigan. Any health routine requires patience and diligence to see the best results. Monolaurin is considered safe to consume in the amounts commonly found in foods. Theoretically, this stops bacteria from replicating and spreading, making it easier for the immune system to destroy them [19]. Although none of the insulin products available for use in dogs and cats have canine- or feline-specific amino acid sequences, anti-insulin antibodies do not appear to cause a significant clinical problem. Dosage form: ophthalmic solution According to another unverified theory, monolaurin breaks down the cell membrane of bacteria, which theoretically makes them easier targets for the immune system. Monolaurin - 500mg, Astragalus - 50mg, Beta Glucan - 50mg, Cat's Claw - 50mg, Olive Leaf - 50mg Directions As a dietary supplement, adults should take one (1) Fat-coated viruses can live in your body fat for years and interfere with your metabolism. Most common hospital and foodborne infections have become resistant to the effects of traditional antibiotics, and people are dying of formerly treatable conditions. A study found that consumption of medium-chain fatty acids such as monolaurin from coconut oil helped in remodeling the gut microbiome by altering the distribution of good bacteria where they were needed the most [Ref #35]. Monolaurin - 500mg, Astragalus - 50mg, Beta Glucan - 50mg, Cat's Claw - 50mg, Olive Leaf - 50mg Directions As a dietary supplement, adults should take one (1) capsule daily or as recommended by a healthcare professional. Roughly 40 to 60% of coconut oil is comprised of lauric acid [38]. Journal of Food Safety 4:1-12 (1982), Goc, A., Niedzwiecki, A. and Rath, M. (2015), In vitro evaluation of antibacterial activity of phytochemicals and micronutrients against Borrelia burgdorferi and Borrelia garinii. About this item. Anyone who is allergic to coconuts should not use coconut oil or monolaurin that has been made from coconut products. When researching and deciding to buy monolaurin, look for purity. From there, he suggests they work their way up to 3000 mg, two to three times per day. Skin and mucosa are known as the barriers against pathogens that the body is exposed to. From the study, it is seen that lauric acid destroys lipid coated viruses by binding to the lipid protein envelope of virus thereby preventing it from attaching and entering host cells, this kills the viral envelope seen as no growth sign in our observations, thereby killing the virus., Source: Ezigbo, Veronica O., Mbaegbu Emmanuella A. Human breast milk is on average 6.2% lauric acid, and breastfeeding provides infants their first introduction to monolaurin. Evidence doesnt support this practice, as clinical data are nonexistent [37, 32]. Dosing Overview Monolaurin is a chemical made from lauric acid, which is found in coconut milk and breast milk. It is also used to treat chronic fatigue syndrome (CFS) and to boost the immune system. "Monolaurin: Benefits, Dosage, and Side Effects". The richest food source of lauric acid is coconut oil, with certain coconut products consisting of nearly 50 percent lauric acid. Monolaurin is used in the food production and cosmetics industries and is also taken as a dietary supplement. Or purchase 3+ of any single product and save! Some people take monolaurin as an immune booster. Monolaurin was active against it in some cell-based studies [32, 27, 33, 34]. At Inspired Nutrition, we have taken those results one step further by increasing the ratio that lauric acid is converted into monolaurin from 3% to 95%. J Appl Microbiol. Treatment of dermal infections with topical coconut oil. One teaspoon of our monolaurin has3,000 mg! Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. FEMS Immunology and Medical Microbiology 36 (2003) p 9-17, Leaky gut syndrome. These are conditions characterised by increased intra-ocular pressure (increased pressure within your eyeballs) due to an imbalance in the production and drainage of the fluid in your eyes. S. Rial, A. Karelis, K. Bergeron, & C. Mounier. Lieberman S, Enig MG, Preuss HG. Monolaurin research suggests it is able to inactivate lipid-coated viruses such as herpes, cytomegalovirus, influenza, and various pathogenic bacteria and protozoa in lab settings [Ref #1, 2, 3, 11, 12]. Available for Android and iOS devices. The recommended dose is one drop of ALPHAGAN P in the affected eye(s) three times daily, approximately 8 hours apart. The recommended dose is one drop of ALPHAGAN P (brimonidine tartrate) in the affected eye (s) three times daily, approximately 8 hours apart. The research on monolaurin is limited. It is not yet known if medicinal amounts of monolaurin are safe. Heres What the Experts Say About Coconut Oil, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 5 Science-Based Benefits of 5-HTP (Plus Dosage and Side Effects), The 15 Best Vitamin Brands of 2023: A Dietitians Picks, Red Raspberry Leaf Tea: Pregnancy, Benefits, and Side Effects, cow and goat milk containing small percentages of lauric acid.