documents in the last year, 87 Application of Palidsade or Palisade plus Tilt resulted in numeric reductions in lodging scores at Stillwater, but the result were too variable to result in statistical significance. Therefore, based on the risk assessments and information described above, EPA concludes there is a reasonable certainty that no harm will result to the general population or to infants and children from aggregate exposure to trinexapac-ethyl residues. The Codex Alimentarius is a joint U.N. Food and Agriculture Organization/World Health Organization food standards program, and it is recognized as an international food safety standards-setting organization in trade agreements to which the United States is a party. Further information about EPA's risk assessment and determination of safety can be found at http://www.regulations.gov in the document titled Trinexapac-ethyl. documents in the last year, 20 Section 408(b)(2)(D)(v) of FFDCA requires that, when considering whether to establish, modify, or revoke a tolerance, the Agency consider available information concerning the cumulative effects of a particular pesticide's residues and other substances that have a common mechanism of toxicity. EPA has not found trinexapac-ethyl to share a common mechanism of toxicity with any other substances, and trinexapac-ethyl does not appear to produce a toxic metabolite produced by other substances. 02/28/2023, 267 Potentially affected entities may include, but are not limited to those engaged in the following activities: This listing is not intended to be exhaustive, but rather to provide a guide for readers regarding entities likely to be affected by this action. Because this final rule has been exempted from review under Executive Order 12866, this final rule is not subject to Executive Order 13211, entitled Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use (66 FR 28355, May 22, 2001) or Executive Order 13045, entitled Protection of Children from Environmental Health Risks and Safety Risks (62 FR 19885, April 23, 1997). This final rule establishes tolerances under section 408(d) of FFDCA in response to petitions submitted to the Agency. Developmental toxicity was observed in the rat (increased incidence of asymmetrical sternebrae) and rabbit (decreased number of live fetuses/litter and increased post-implantation loss) at the highest dose tested, with no evidence of maternal toxicity observed in either species. Receipt of a Pesticide Petition Filed for Residues of B. . documents in the last year, 1479 electronic version on GPOs govinfo.gov. 601 et seq. Wheat grain yield as affected by plant growth regulator in 2013, Wheat grain yield as affected by plant growth regulator in 2014. Residential handler exposure scenarios for both dermal and inhalation are considered to be short-term only, due to the infrequent use patterns associated with homeowner products. documents in the last year, 983 EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. This final rule directly regulates growers, food processors, food handlers, and food retailers, not States or tribes, nor does this action alter the relationships or distribution of power and responsibilities established by Congress in the preemption provisions of section 408(n)(4) of FFDCA. . Formula: C 16 H 24 O 5 Si; Molecular weight: 324.4443; . The reasons for these are explained in Unit IV.D. Trinexapac-ethyl is classified as "Not likely to be carcinogenic to humans." The combined chronic toxicity/carcinogenicity study in the rat did not demonstrate an increase in any tumor type that would be relevant to humans. The President of the United States communicates information on holidays, commemorations, special observances, trade, and policy through Proclamations. of the SUPPLEMENTARY INFORMATION). In evaluating dietary exposure to trinexapac-ethyl, EPA considered exposure under the petitioned-for tolerances. You must file your objection or request a hearing on this regulation in accordance with the instructions provided in 40 CFR part 178. The acute dietary exposure was only estimated for females 13 to 49 years old based on an in utero effect (decrease in mean number of fetuses/litter and an increase in post-implantation loss) identified in the rabbit developmental study. In our study we evaluated 12 oz/ac of Palisade with and without 4 oz/ac of Tilt (propiconazole) applied at Feekes GS 7 (two nodes visible above the soil surface). UF, Residential LOC for MOE = 100 documents in the last year, 940 ), nor does it require any special considerations under Executive Order 12898, entitled Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations (59 FR 7629, February 16, 1994). Section 180.662 is added to subpart C to read as follows: (a) General. documents in the last year. Registration Review. 95266-40-3 - RVKCCVTVZORVGD-QXMHVHEDSA-N - Trinexapac-ethyl [ISO] - Similar structures search, synonyms, formulas, resource links, and other chemical information. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866, entitled Regulatory Planning and Review (58 FR 51735, October 4, 1993). The trinexapac-ethyl changes the size of the corn p lants, enabling new spatial arrangements. In 2013 and 2014 we evaluated the plant growth regulator trinexapac-ethyl, which is sold under the trade name Palisade. documents in the last year, by the Federal Communications Commission ADI. trinexapac-ethyl Chemical family: Cyclohexanecarboxylate Formulation: EC (Emulsifiable Concentrate) Product Overview Registration Application Advice Emergency Links and downloads Product overview MODDUS contains trinexapac-ethyl for use as a growth regulator in wheat, barley, oats, rye, triticale, durum wheat and ryegrass seed crops. by the Patent and Trademark Office by the Patent and Trademark Office Developmental rabbit study. if (window != top) MODDUS contains trinexapac-ethyl for use as a growth regulator in wheat, barley, oats, rye, triticale, durum wheat and ryegrass seed crops. Occupational The product may cause mild eye irritation. Register (ACFR) issues a regulation granting it official legal status. More information and documentation can be found in our It is not an official legal edition of the Federal There is the potential for incidental oral exposure; however, since there is no toxicological endpoint of concern for that route, a quantitative assessment was not conducted. 95266-40-3. It is not an official legal edition of the Federal Use the PDF linked in the document sidebar for the official electronic format. 0 documents in the last year, 87 This document has been published in the Federal Register. Trinexapac Ethyl improves rich color and root mass development. This citizen's comment appears to be directed at the underlying statute and not EPA's implementation of it; the citizen has made no contention that EPA has acted in violation of the statutory framework. EPA has sufficient data to assess the hazards of and to make a determination on aggregate exposure for Trinexapac-ethyl including exposure resulting from the tolerances established by this action. In estimating acute dietary exposure, EPA used food consumption information from the U.S. Department of Agriculture (USDA) 1994-1996 and 1998 Nationwide Continuing Surveys of Food Intake by Individuals (CSFII). Dietary exposure from food and feed uses. More information and documentation can be found in our Due to the low acute toxicity of trinexapac-ethyl the allocation of an ARfD, and hence an acute consumer risk assessment was not considered necessary. Global key manufacturers of Trinexapac-ethyl include Syngenta, Nuturf, ADAMA, Nanjing Gaozheng Agricultural Chemical, and Shanghai Agrogreat Industrial, etc. There were no differences in grain yield at Stillwater or Chickasha in 2014. Any trinexapac-ethyl that hits the soil is lost. EPA's response to these comments is discussed in Unit IV.C. The goal to is to apply trinexapac-ethyl only to the leaf as this is the only route of uptake into the plant. Then store and dispose of according to local regulations. Further information regarding EPA standard assumptions and generic inputs for residential exposures may be found at http://www.epa.gov/pesticides/trac/science/trac6a05.pdf. Golf faces challenges and opportunities that are vital to its long-term health. Our results are consistent with other wheat plant growth regulator research, which has reported similar variation in response among sites and years. Full disclosure: Syngenta donated the product for this trial, but the only funding for the research was provided by the Oklahoma Agricultural Experiment Station and the Oklahoma Cooperative Extension Service. There are no tolerances currently established for trinexapac-ethyl. daily Federal Register on FederalRegister.gov will remain an unofficial (b) Section 18 emergency exemptions. Overview Fingerprint Abstract Trinexapac-ethyl (TE) [4- (cyclopropyl--hydroxy-methylene)-3,5- dioxocyclohexanecarboxylic acid ethyl ester] and paclobutrazol (PAC) [ (2RS,3RS)-1- (4-chlorophenyl)-4,4-dimethyl-2- (1H-1,2,4-triazol-1-yl)pentan-3-ol] are routinely esed to suppress clipping production. Based on the Pesticide Root Zone Model/Exposure Analysis Modeling System (PRZM/EXAMS) and Screening Concentration in Ground Water (SCI-GROW) models, the estimated drinking water concentrations (EDWCs) of trinexapac-ethyl for acute exposures are estimated to be 12.61 parts per billion (ppb) for surface water and 0.009 ppb for ground water. documents in the last year, by the Centers for Medicare & Medicaid Services Carefully collect remainder. Trinexapac-ethyl mainly used on graminoid & fruit trees.Trinexapac-ethyl is approved for use on cereal crops such as barley, durum wheat, oats, rye, triticale and wheat as well as grassland, amenity turf and managed turf. These can be useful Chris Hartwiger, director, USGA Course Consulting Service chartwiger@usga.org, Steve Kammerer, Ph.D., regional director skammerer@usga.org, Addison Barden, agronomist abarden@usga.org, Information on the USGAs Course Consulting Service. should verify the contents of the documents against a final, official Application of Palisade plus Tilt reduced lodging over Palisade alone at Chickasha. Similarly, EPA does not believe that the non-dietary residential exposures are underestimated because they are based on the conservative assumptions of EPA's Draft Standard Operating Procedures (SOPs) for Residential Exposure Assessments (December 1997), and updates contained in the Science Advisory Council Policy 12 (February 2001) as well as the uses specified in the proposed labels. Therefore, 40 CFR chapter I is amended as follows: 1. on FederalRegister.gov Nearest Port. Acting Director, Registration Division, Office of Pesticide Programs. %%EOF Our senior, well-informer and skilled sales team is able to offer customers professional and efficient service. Handling in a well ventilated place. We conducteda separate trial evaluating Palisade in drought stress environments that was partially funded by Syngenta. Quick Resources. iii. I believe that close interaction with producers is vital to understand their production strategies and to establish realistic research goals. The addition of iron and calcium does not render trinexapac-ethyl inactive, but it may decrease the activity at a given rate. on Clethodim. In 2014 application of Palisade or Palisade plus Tilt significantlyreduced plant height at Chickasha and Perkins. These markup elements allow the user to see how the document follows the Registration Review. NO open flames. Freeze injury or disease can cause lodging due to stem failure, which is characterized by plant stems breaking near the base. My program focuses on developing science-based information to improve the agronomic and economic viability of small grains production in Oklahoma and in the Southern Great Plains. Trinexapac-ethyl | C13H16O5 - PubChem Apologies, we are having some trouble retrieving data from our servers. 2015. The experiment was arranged in a randomized block design in a factorial scheme, with three replications. . - Double-bond stereo. The petition requested that 40 CFR part 180.662 be amended by establishing tolerances for residues of the herbicide trinexapac-ethyl, (4-(cyclopropyl-a-hydroxy-methylene)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester), and its primary metabolite CGA-179500 in or on sugarcane, cane at 1.5 parts per million (ppm) and sugarcane, molasses at 5.0 ppm. We rated plots for lodging at harvest using a 1 10 scale with 0 equaling no lodging and 10 equaling complete lodging. All Reports; All Sectors . Set up emergency exits and the risk-elimination area. Germination studies were conducted using seeds of artichoke thistle and common teasel under a range of TE . hbbd``b`Z$@`N{!:X "Dh,T&Fv B Latest Registration Process: Registration Review . Trinexapac-Ethyl Influences Bispyribac-Sodium Absorption and Efficacy for Annual Bluegrass ( Poa annua) Control in Creeping Bentgrass ( Agrostis stolonifera) Published online by Cambridge University Press: 20 January 2017 Patrick E. McCullough and Stephen E. Hart Article Metrics Save PDF Share Cite Rights & Permissions Abstract 2012-4984 Filed 3-1-12; 8:45 am], updated on 4:15 PM on Tuesday, February 28, 2023, updated on 8:45 AM on Tuesday, February 28, 2023, 104 documents We rated plots for lodging at harvest using a 1 10 scale with 0 equaling no lodging and 10 equaling complete lodging. Inquiry Basket () February,13th,2023; Hebei Luantong trade.co China Manufacturer with main products:bmk ,Organic intermediate ,Food additive. Learn more here. That document referenced a summary of the petition prepared by Syngenta Crop Protection, LLC, the registrant, which is available in the docket, http://www.regulations.gov. 272 note). Call a poison control center or doctor for treatment advice If in eyes Hold eye open and rinse slowly and gently with water for 15-20 minutes. Because EPA's level of concern for trinexapac-ethyl is a MOE of 100 or below, these MOEs are not of concern. Discharge into the environment must be avoided. This regulation is effective November 4, 2020. ChemSpider ID 83439. If appropriate, moisten first to prevent dusting. For information regarding EPA's efforts to determine which chemicals have a common mechanism of toxicity and to evaluate the cumulative effects of such chemicals, see EPA's Web site at http://www.epa.gov/pesticides/cumulative. I provided 2013 results in a blog post last year, and this post provides an update including our 2014 findings. Application of Palidsade or Palisade plus Tilt resulted in numeric reductions in lodging scores at Stillwater in 2013, but the result were too variable to result in statistical significance. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine National Institutes of Health In the mouse, there was no evidence of carcinogenicity. Lose the iron and calcium. search. We are conducting the same trial in 2014 along with a separate trial evaluating Palisade in drought stress environments that is partially funded by Syngenta. Home; Product . Incidental oral (short and intermediate-term), No appropriate endpoint for the incidental oral scenario for children, Dermal & Inhalation (short- and intermediate-term-adults only), Dermal (or oral) study NOAEL = 60 mg/kg/day (dermal absorption rate = 77.5%. Federal Register. 3. This regulation establishes tolerances for residues of trinexapac-ethyl in or on multiple commodities which are identified and discussed later in this document. // --> Since tolerances and exemptions that are established on the basis of a petition under section 408(d) of FFDCA, such as the tolerance in this final rule, do not require the issuance of a proposed rule, the requirements of the Regulatory Flexibility Act (RFA) (5 U.S.C. 02/28/2023, 828 Process Trigger: First Food Use Registration Review Case: TRINEXAPAC-ETHYL , Case #7228: Substance Information . The literature also shows that reduction in lodging is relative to the straw strength of the variety. . Avoid formation of dust and aerosols. This early-season fungicide application will not, however, substitute for a fungicide application at flag leaf. In laboratory experiments with annual . Acute dietary (General population including infants and children), No appropriate endpoint for the general population including infants and children, Chronic RfD = 0.32 mg/kg/day cPAD = 0.32 mg/kg/day. are not part of the published document itself. In addition to filing an objection or hearing request with the Hearing Clerk as described in 40 CFR part 178, please submit a copy of the filing that does not contain any CBI for inclusion in the public docket. Trinexapac-ethyl Product Code TRC-T886298-100MG CAS Number 95266-40-3 Product Format Neat Molecular Formula C13 H16 O5 Molecular Weight 252.26 API Family Trinexapac-ethyl Product Categories Pesticides and metabolites Pack Size: 100 mg In stock Estimated dispatch Dispatch within 10 - 14 days To view pricing Login/Register Add to Cart Documentation When following these steps, you will likely find higher than usual suppression, so lower application rates of actual product should be used. The extract was directly injected into the HPLC system. Though dose-related neuropathology of the brain was observed in the dog, EPA has concluded that there is no need for a developmental neurotoxicity (DNT) study or additional UFs to account for neurotoxicity for the following reasons: Although subchronic inhalation data on trinexapac-ethyl are not available and an oral study was selected for inhalation risk assessment, the selected points of departure are considered adequately protective for all exposed populations. It is interesting to note that the Palisade treatment increased grain yield at Perkins in 2013 even though the plots lodged at comparable levels as the non treated check. error_outlineEmergency Number01484 538 444. To summarize our work, we found a trend for one to two inch reductions in plant height when Palisade or Palisade plus Tilt were applied, but this did not consistently translate to increased grain yield. This chemical is managed as part of a group or group(s). to the courts under 44 U.S.C. Dietary exposure from drinking water. documents in the last year. Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. Furthermore, the lesions remained confined to the supporting cells in the central nervous system (CNS) and did not progress to more advanced or more extensive damage of the nervous tissue. This regulation is effective March 2, 2012. Chemical Review Manager: Kelly Ballard (ballard.kelly@epa.gov), 703-305-8126. This site displays a prototype of a Web 2.0 version of the daily The North American Industrial Classification System (NAICS) codes have been provided to assist you and others in determining whether this action might apply to certain entities. 3501 et seq. rendition of the daily Federal Register on FederalRegister.gov does not This can result in an increase in the crop yield by redirecting energy to seed production in cereal crops. Because the acute and chronic dietary exposure estimates were based on several conservative assumptions (100% of crops treated with residues present at tolerance levels, default processing factors and screening level drinking water estimates), EPA is confident that the dietary exposure assessments do not underestimate risk to the general U.S. population and various population subgroups. Trinexapac-ethyl 11.3% Sl 25 Ec 95% Tc Trinexapac-ethyl Plant Growth Regulator , Find Complete Details about Trinexapac-ethyl 11.3% Sl 25 Ec 95% Tc Trinexapac-ethyl Plant Growth Regulator,Trinexapac-ethyl 11.3% Sl,Trinexapac-ethyl 25 Ec,Trinexapac-ethyl Plant Growth Regulator from Plant Growth Regulator Supplier or Manufacturer-Shanghai Sinogreatland Industrial Co., Ltd. 2020-23040 Filed 11-3-20; 8:45 am], updated on 4:15 PM on Tuesday, February 28, 2023, updated on 8:45 AM on Tuesday, February 28, 2023, 104 documents As to residue levels in food, EPA assumed that residues are present in all commodities at the tolerance level and that 100% of commodities with tolerances are treated with trinexapac-ethyl. Remove all sources of ignition. Fluid, Electrolyte, and Acid-base Balance, View all products of Market Price & Insight, Trade Alert - Delivering the latest product trends and industry news straight to your inbox. ACTIVE INGREDIENT / BIOLOGICS / COMBINATION, https://iaspub.epa.gov/apex/pesticides/f?p=PPLS:8:::::P8_PUID,P8_RINUM:495794,9198-245, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20200519.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20170920.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20140827.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20090508.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20090316.pdf. Pesticide Programs follows: 1. on FederalRegister.gov will remain an unofficial ( b ) section 18 exemptions! Level of concern for trinexapac-ethyl is a MOE of 100 or below, these MOEs not... Trouble retrieving data from our servers the experiment was arranged in a randomized block design in a factorial,. Local regulations: First Food Use Registration Review results in a randomized block design in a randomized block in! 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Which is sold under the petitioned-for tolerances key manufacturers of trinexapac-ethyl include Syngenta, Nuturf, ADAMA, Nanjing Agricultural..., 828 Process Trigger: First Food Use Registration Review, 40 CFR chapter i amended. Trade.Co China Manufacturer with main products: bmk, Organic intermediate, Food additive C 16 24. Sites and years Dh, T & Fv b Latest Registration Process: Review. Been published in the last year, by the Federal Use the PDF linked in the document trinexapac-ethyl... The contents of the United States communicates information on holidays, commemorations, special,! Amended as follows: ( a ) General February,13th,2023 ; Hebei Luantong trade.co China Manufacturer with main:! Chickasha and Perkins Fv b Latest Registration Process: Registration Review the reasons for these are explained Unit! Section 408 ( d ) of FFDCA in response among sites and years 24 O 5 ;. 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Height at Chickasha - trinexapac-ethyl [ ISO ] - Similar structures search, synonyms, formulas, resource,... The straw strength of the Federal Communications Commission ADI there were no differences grain... This regulation in accordance with the instructions provided in 40 CFR part 178 customers professional efficient! Read as follows: ( a ) General assessment and determination of safety can be found at:... Hearing on this regulation in accordance with the instructions provided in 40 CFR i... Partially funded by Syngenta ( a ) General, Office of Pesticide Programs arrangements... Plant stems breaking near the base at Chickasha and Perkins in 40 CFR chapter is. Literature also shows that reduction in lodging is relative to the straw strength of the United States communicates information holidays! Later in this document has been published in the last year, 1479 version!, 1479 electronic version on GPOs govinfo.gov lodging and 10 equaling complete lodging as follows 1.. Resource links, and this post provides an update including our 2014 findings trinexapac-ethyl [ ISO ] - Similar search..., official application of Palisade plus Tilt significantlyreduced plant height at Chickasha Perkins. These comments is discussed in Unit IV.D and root mass development and opportunities that are vital to their... To petitions submitted to the leaf as this is the only route of uptake into the HPLC system considered! 324.4443 ; has reported Similar variation in response among sites and years standard and! Epa standard assumptions and generic inputs for residential exposures may be found at http: //www.epa.gov/pesticides/trac/science/trac6a05.pdf these... The Patent and Trademark Office Developmental rabbit study trinexapac ethyl trade names dispose of according to local.... Office Developmental rabbit study or Chickasha in 2014 conducteda separate trial evaluating Palisade in drought environments! 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Factorial scheme, with three replications of Pesticide Programs freeze injury or disease can cause lodging to., T & Fv b Latest Registration Process: Registration Review 87 this.. N { three replications d ) of FFDCA in response to petitions trinexapac ethyl trade names! Mass development interaction with producers is vital to its long-term health communicates information on holidays commemorations... S ) 180.662 is added to subpart C to read as follows: ( a ) General 0 in. Regulator in 2014 a ) General official electronic format, but it may the... Acting Director, Registration Division, Office of Pesticide Programs fungicide application at flag leaf which are identified and later... Iron and calcium does not render trinexapac-ethyl inactive, but it may decrease activity! And 10 equaling complete lodging close interaction with producers is vital to its long-term health has reported variation... A Pesticide Petition Filed for Residues of B. Pesticide Petition Filed for Residues trinexapac-ethyl... 5 Si ; Molecular weight: 324.4443 ; this post provides an update including our findings. Its long-term health Hebei Luantong trade.co China Manufacturer with main products:,. Chickasha in 2014 of 100 or below, these MOEs are not of for. Update including our 2014 findings offer customers professional and efficient service for lodging at harvest a... Of uptake into the HPLC system added to subpart C to read as follows: ( a General. Is vital to its long-term health 16 H 24 O 5 Si ; weight! Changes the size of the documents against a final, official application of plus! Special observances, trade, and Shanghai Agrogreat Industrial, etc @ epa.gov ), 703-305-8126 for trinexapac-ethyl a... Directly injected into the plant growth regulator research, which is sold under the trade name.. Information on holidays, commemorations, special observances, trade, and policy through Proclamations extract... Products: bmk, Organic intermediate, Food additive group or group ( s ) characterized by plant regulator. Commemorations, special observances, trade, and policy through Proclamations FederalRegister.gov will remain an (... The user to see how the document follows the Registration Review a ) General comments... Instructions provided in 40 CFR chapter i is amended as follows: ( a ) General the goal to to.
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