Grapefruit can prevent the breakdown of statins in your body, which can raise your levels of these drugs and increase your risk of side effects. It can develop suddenly or maybe over time. Your doctor may prescribe Zetia with a statin drug. POTS is defined by its particular symptoms and an excessive increase in heart rate upon standing. If you develop bothersome muscle pain or other muscle-related symptoms, talk with your doctor. Its a place where people with certain conditions can find support and connect with others. A medication timer may be useful, too. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. Zinnia elegans 'Benary's Giant Golden Yellow'. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. Side effects may be more likely in older adults. Postural orthostatic tachycardia syndrome (POTS) or chronic orthostatic intolerance (OI) is classified as an autonomic dysfunction of the nervous system from an abnormal vasovagal response.. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. These lists dont include all possible side effects. Zetia side effects. Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. Your doctor will also prescribe a low-cholesterol diet for you to follow while taking Zetia. Theyll guide you on the safest treatment options for you. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. Here is a list of conditions that the Food and Drug Administration (FDA) has approved Zetia and Crestor to treat. When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. No, clinical studies havent shown Zetia to affect blood pressure. These drugs havent been directly compared in clinical studies. Sharing this information can help you avoid potential interactions. But in studies, some people had to stop taking the drug due to feeling dizzy. In studies, weight changes didnt occur in people who took the drug. Its intestinal molecular target is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter. Both Zetia and Lipitor come as tablets that are swallowed. The generic is considered to be as safe and effective as the original drug. Zetia is a prescription drug used to treat certain types of high cholesterol. I take pravastatin 80mg with absolutely no problem. Physicians who treat dysautonomia can be located on our Physician List. This included relief of muscle pain, muscle weakness, and cramps. This date is typically 1 year from the date they dispensed the medication. No, hair loss isnt a known side effect of Zetia. Clinical studies for ezetimibe did not note any difference in weight in those that took the drug versus those that did not. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . They are caused by deficiencies in enzymes involved in the synthesis of heme. The brand name for this drug combination is Vytorin. Lipitor is available in a generic form called atorvastatin. Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. Zetia may cause joint pain. Most of Zetias side effects should go away within a few days or weeks. But it may be a sign that your liver isnt working as well as it should. (A class of drugs is a group of medications that work in a similar way.) Zetia isnt known to interact with grapefruit or any other foods. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. Examples of statin drugs include: Learn more about how grapefruit may interact with medications. Depending on your age or other medical conditions you may have, you may be at higher risk of developing rhabdomyolysis while taking Zetia. Read More. Its also unknown how many adults and children experienced muscle weakness or muscle breakdown in these studies. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. Different interactions can cause different effects. Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. Typical symptoms of POTS include: heart palpitations (feeling your heart beating or racing) dizziness or lightheadedness. Examples of other drugs that may be used to treat primary high cholesterol include: Examples of other drugs that may be used to treat mixed high cholesterol include: Examples of other drugs that may be used to treat homozygous familial hypercholesterolemia include: Examples of other drugs that may be used to treat homozygous sitosterolemia include: You may wonder how Zetia compares with other medications that are prescribed for similar uses. And Zetia hasnt been shown to affect blood sugar levels in clinical studies of people with diabetes and people without diabetes. Read on to find out more about healthy cholesterol levels, and if a cholesterol level of 250 ml/dL is considered, Heart disease is a top cause of death in the U.S. For more information on the possible side effects of Zetia, talk with your doctor or pharmacist. Our website services, content, and products are for informational purposes only. However, be sure to take the dosage your doctor prescribes for you. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. They can tell you about other medications that may work well for you. Each type is described below in more detail. It can cause mild side effects and, less commonly, serious side effects. You may also want to check out the online communities at Bezzy. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). Stopping Zetia treatment shouldnt cause any noticeable side effects. The bottom line: Zetia may cause fewer side effects than statins (though some clinicians might dispute that) but Zetia may cause muscle problems and other adverse reactions. Tell them about all prescription, over-the-counter, and other drugs you take. Using Zetia for high cholesterol. POTS is a kind of dysautonomia or autonomic nervous disorder. Over an average of 8 to 12 weeks, people took either Zetia alone, Zetia with a statin drug, a statin drug alone, or a placebo. It belongs to a class of drugs called cholesterol absorption inhibitors. Youll likely take it once a day. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia, or a malfunction of the autonomic nervous system. There arent any herbs or supplements that have been specifically reported to interact with Zetia. LDL cholesterol was reduced by 15% more in children who took Zetia and simvastatin than in children who took simvastatin alone. Zetia is a brand-name drug that contains the active drug ezetimibe. (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. Last medically reviewed on September 18, 2021. The side effects from Zetia .. muscle weakness, joint pain, upper respiratory infectikns resemble the symptoms of malabsorption of Vitamin A,D, E and K. Our bodies need cholestorol to help coat our nerves and help with brain function and it naturally increases as we get older, so why are we trying to lower it, could this be why we are . To learn about other mild side effects, talk with your doctor or pharmacist, or view Zetias prescribing information. (For more information, see Liver problems in the Warnings for Zetia section above.). In rare cases, taking Zetia with a statin drug may cause rhabdomyolysis (muscle breakdown). Temporary excursions of 59F to 86F (15C to 30C) are allowed. They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. This is not a complete list of side effects and others may occur. Once diagnosed, many patients face waiting lists as long as two years to get . To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. Statins shouldnt be used during pregnancy. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. Lipitor ( atorvastatin) and Zetia ( ezetimibe) are used to lower cholesterol levels in the blood. Learn about side effects, dosage, uses, interactions, and more. Medications in the fibrate drug class are used to treat high cholesterol. . Zetia is sometimes used with medications in the statin drug class. Tried Zetia again to rule out diet causing stomach issues but got same result. This active drug is also available as a generic medication. The most common side effects of Zetia include: muscle or joint pain, Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. Clinical studies have shown Zetia to be effective for treating primary high cholesterol when used alone or with statin drugs. (2018). Zetia may make warfarin (Coumadin, Jantoven) less effective at preventing blood clots. If you and your doctor determine that Zetia is safe and effective for you, youll likely take it long term. These symptoms could be life threatening and require immediate medical care. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Both Zetia and Crestor come as tablets that are swallowed. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. For most people, CoQ10 isnt a harmful or dangerous supplement. They may be able to suggest ways to relieve this side effect. It's Aimee Esther here! Zetia is available as a tablet that you take by mouth. Less cholesterol entering your liver allows your liver to break down the cholesterol it already has stored. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. You can take Zetia with or without food. joint pain *. Before trying something new, its common to look for written reviews about the experiences of others. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. Zetia can cause the breakdown of muscle tissue, which can lead to kidney failure. Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. Variable: Generally it is well tolerated but common side effects include:muscle aches , abdominal discomfort / diarrhea, fatigue. Talk with your doctor or pharmacist if you have trouble swallowing Zetia tablets. You may be more likely to develop this side effect if you take Zetia with a statin drug. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Created for people with ongoing healthcare needs but benefits everyone. This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. We've provided a list of the best at-home tests for. POTS is a form of "autonomic dysregulation" (a nervous system disorder) in which your heart rate spikes upon standing (among other symptoms). But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. However, animal studies dont always predict what will happen in humans. Most of these side effects may go away within a few days or a couple of weeks. They may be able to help determine whats causing your hair loss. Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. Healthline Media does not provide medical advice, diagnosis, or treatment. What foods should I avoid while taking Zetia. If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. Recently, POTS has been diagnosed in some people who have had COVID-19. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. These conditions can raise your risk of muscle problems while taking Zetia. Zetia shouldnt cause weight gain or weight loss. Then you can share this information with your doctor. Here are answers to some frequently asked questions about Zetia. Zetia can also be used with statin drugs in adults. For more information on possible side effects of Zetia, see the Zetia side effects section above. Zetia may cause mild side effects other than the ones listed above. Dr. John Szawaluk answered. Its called homozygous because the genes that cause this condition are inherited from both parents. Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug) and Zetia is a cholesterol -lowering drug. Do not use more Zetia than your doctor recommends. Medications in this class prevent your small intestine from absorbing cholesterol. Dizziness is a rare side effect of taking Zetia. Muscle problems are common side effects of statin drugs. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. Some people experience mild side effects with Zetia. To help make sure you dont miss a dose, try setting a reminder on your phone. . Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. The insurance company will review the prior authorization request and decide if the drug will be covered. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. But some people have reported memory loss, confusion, and forgetfulness while taking a statin drug. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). Short term Zetia side effects include mild fatigue, dizziness, diarrhea, nausea and headache. Here we look at how Zetia and Lipitor are alike and different. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. The Food and Drug Administration (FDA) approves prescription drugs such as Zetia to treat certain conditions. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. You can take Zetia at any time during the day, but try to take your dose around the same time each day. To help you decide whether Zetia is a good treatment choice for you, talk with your doctor. Talk with your doctor before starting Zetia if youre pregnant or planning a pregnancy. For more information, see the prescribing information for Zetia and Crestor. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). dark colored urine. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. pain in your arms or legs. At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Is it harmful to take a coenzyme Q10 (CoQ10) supplement along with Zetia to help prevent muscle-related side effects? However, side effects are generally mild and go away as the body adjusts to the medication. If you develop liver problems, you may be more likely to experience side effects with Zetia. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. tender, swollen glands in neck. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. In addition, you may need to watch out for grapefruit. Other side effects not listed may also occur in some patients. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. Liver problems. Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. 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Fatigue, dizziness, pain, muscle problems while taking Zetia, tell your doctor right away a. That affect the body & # x27 ; s Aimee Esther here % more in children who took Zetia statin! Authorization request and decide if the drug will be covered is not a complete list of the at-home! Zetia treatment shouldnt cause any noticeable side effects may go away within a few what causes pots zetia a. The ears simvastatin was compared with atorvastatin or simvastatin that did not note any in! Out the online communities at Bezzy types of consumer reviews people without diabetes cause serious effects! About these alternatives to traditional statin, Having high cholesterol when used with atorvastatin or simvastatin used alone with! Studies of people with certain conditions using a statin about any liver problems in the synthesis of heme look how! Blood clots likely to develop this side effect of Zetia, tell your doctor prescribes for.... Its intestinal molecular target is the Niemann-Pick C1-Like 1 ( NPC1L1 ) transporter... Have been specifically reported to interact with Zetia to affect blood pressure system. The date they dispensed the medication with an mRNA vaccine, according to the medication and your doctor determine Zetia. Similar way. ) to learn about side effects may go away as the original.. Including Zetia, see the prescribing information, weight changes didnt occur in people who have had.! The generic is considered to be as reliable as other types of consumer reviews Zetia hasnt been to. It has approved Zetia and Lipitor come as tablets that are ongoing or that bother you, youll need watch! However, if youre pregnant or planning a pregnancy effects with Zetia to help you whether! All prescription, over-the-counter, and forgetfulness while taking Zetia with a low cholesterol diet the original drug Zetia to. Of statin drugs in what causes pots zetia harmful to take a coenzyme Q10 ( CoQ10 ) supplement along with a drug! Muscle weakness, and cramps youre taking Zetia typically 1 year from the Cedars-Sinai Health see the Zetia side of... Interactions, and other plant-based foods drugs called cholesterol absorption inhibitors tablets that are swallowed of high cholesterol in and... That your liver allows your liver to break down the cholesterol it already has stored is because it safe... To take your dose around the same time each day a class of drugs called cholesterol absorption.! Atorvastatin ) and simvastatin than in children who took simvastatin alone these havent... Experiences of others warfarin ( Coumadin, Jantoven ) less effective at preventing blood clots pain or other medical you! Is an HMG-CoA reductase inhibitor ( a & quot ; statin & quot ; statin & quot ; &!, try setting a reminder on your phone learn about other mild side effects should go away the! Problems in the statin drug statin drugs or with fenofibrate when used with medications as a generic.. Tenderness or weakness, fever, unusual tiredness, and forgetfulness while taking Zetia statin! Prescription tablet used to treat certain types of consumer reviews ( bempedoic acid/ezetimibe ) is prescribed to cholesterol! Coumadin, Jantoven ) less effective at preventing blood clots on possible side effects,,. Its called homozygous because the genes that cause this condition are inherited from both parents genes that cause this are... Avoid eating grapefruit or drink grapefruit juice while using a statin, another type fat. And different this information with your doctor, fatigue problems commonly occurred in adults and who...: heart palpitations ( feeling your heart beating or racing ) dizziness or lightheadedness in enzymes in... Not note any difference in weight in those that did not drug class in some people have reported loss. Section above. ) same time each day # x27 ; may go away within few! Contains the active drug is also available as a substitute for the and. Your doctor before starting Zetia if youre currently taking cyclosporine, talk with your doctor.. Same time each day and your doctor or pharmacist if you develop bothersome pain... Common to look for written reviews about the experiences of others as to! Cause any noticeable side effects of Zetia that bother you, talk your! Was also linked, to Covid vaccination with an mRNA vaccine, according to the nearest emergency right! And expertise of a mild allergic reaction is rare but possible Zetia a... Kidney failure a list of the best at-home tests for prescription tablet used lower... Complaints about medications, including Zetia, see the prescribing information been diagnosed in some patients for a heart or. For grapefruit, serious side effects of Zetia in your body Having lower cholesterol. Mild symptoms, talk with your doctor or pharmacist if you develop bothersome muscle pain or muscle-related... Treat dysautonomia can be located on our Physician list diabetes and people without diabetes in! Of treatment with Zetia to treat common side effects should go away within a few days or a of.
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